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Thoughts and ideas from Dr Lola Adeyemi
"Addressing the Disparities in Clinical Trials: Strategies and Success Stories"
January 2, 2023 at 5:00 AM
by Dr Lola Adeyemi
"Addressing the Disparities in Clinical Trials: Strategies and Success Stories"

Clinical trials are essential for developing new treatments and advancing healthcare. However, these trials are not always representative of the diverse patient population they are intended to serve, leading to disparities in healthcare outcomes. Racial and ethnic minorities, women, older adults, and individuals from low-income communities are often underrepresented in clinical trials. In this article, we explore the issue of disparities in clinical trials and highlight strategies and success stories in addressing this problem.

The statistics on disparities in clinical trials are staggering. According to a study by the Food and Drug Administration (FDA), African Americans make up only 5% of clinical trial participants, despite representing 13% of the US population. Hispanics are similarly underrepresented, making up only 1% to 6% of clinical trial participants. According to a report in the Washington post, Women are also underrepresented, accounting for only 39% of clinical trial participants. Older adults are often excluded from clinical trials, despite being the largest consumer of healthcare services.

Before we highlight the implications and strategies to address these disparities we should pay attention to the drivers that brought us here. The Institute of Medicine. 2003. Unequal Treatment: Confronting Racial and Ethnic Disparities in Health Care. highlighted many of these issues and strategies in which to address them.

These disparities in clinical trials have serious implications for healthcare outcomes. For example, African Americans have a higher incidence of certain cancers, but are less likely to participate in clinical trials for cancer treatments. This means that there is limited understanding of how these treatments work in African American patients, which can result in disparities in healthcare outcomes. Similarly, women are often excluded from clinical trials for cardiovascular disease, even though heart disease is the leading cause of death in women in the United States.

To address these disparities, there are several strategies that can be employed. One approach is to increase outreach and education efforts to underrepresented communities. For example, the FDA has launched campaigns to increase participation of African Americans and Hispanics in clinical trials. These campaigns provide information about the benefits and risks of clinical trials and encourage participation in research.

Another strategy is to prioritize diversity in clinical trial design and recruitment. This means designing clinical trials that are representative of the patient population they are intended to serve. For example, the National Institute of Health (NIH's) All of Us Research Program is designed to include a diverse group of participants, including individuals from underrepresented communities. This approach ensures that research findings are more applicable to a wider population.

A strategy that has not been prioritized is the strength of a diverse healthcare workforce. In particular the pipeline of diverse healthcare workers along the clinical trial journey. Research has shown that there is a longer life expectancy and lower mortality in black populations with a higher prevalence of black doctors.

Success stories in addressing disparities in clinical trials include the development of new treatments for rare diseases. For example, Spinraza, a treatment for spinal muscular atrophy, was developed with the help of patients and patient advocacy groups; Cure SMA provided the first research funding needed to begin investigation into this therapeutic approach. By engaging patients and their families in the clinical trial process, the researchers were able to design a trial that was more representative of the patient population.

Addressing disparities in clinical trials is critical to advancing healthcare and reducing disparities in healthcare outcomes. By increasing outreach and education efforts, prioritizing diversity in clinical trial design and recruitment, and engaging patients and patient advocacy groups, we can ensure that clinical trials are more representative of the diverse patient population they are intended to serve. Through these efforts, we can work towards closing the gap in healthcare outcomes and improving the lives of all patients.

What are you doing towards achieving health equity in clinical trials? It takes a village so let's collaborate!

“Why the Pharmaceuticals and Biotech Industries Should Prioritize Health Equity"
September 1, 2022 at 4:00 AM
by Dr. Lola Adeyemi
“Why the Pharmaceuticals and Biotech Industries Should Prioritize Health Equity"

The pharmaceutical and biotech industries have made tremendous contributions to improving human health by developing new treatments, drugs, and vaccines. However, there is still a significant gap in healthcare outcomes between different racial, ethnic, and socioeconomic groups. This gap is due, in part, to the lack of representation of diverse populations in clinical trials and the high cost of many life-saving treatments. As a result, there is an urgent need for the pharmaceuticals and biotech industries to prioritize health equity.

The statistics are clear: racial and ethnic minorities have higher rates of chronic diseases, such as diabetes and heart disease, and are less likely to have access to preventive care and effective treatments. For example, according to the U.S Health and Human Services, OMH African Americans are 60% more likely to have diabetes than non-Hispanic whites, and Hispanic Americans are nearly twice as likely to die from liver disease as non-Hispanic whites. These disparities are not only unjust but also have significant economic consequences. According to a 2018 study by the W.K. Kellogg Foundation and Altarum the cost of health inequities in the US is estimated to be $93 billion per year.

One solution is to increase the representation of diverse populations in clinical trials. Currently, most clinical trials are conducted in wealthy, developed countries, with limited participation from low-income countries and minority populations. By recruiting more diverse participants, pharmaceutical and biotech companies can ensure that their products are effective for all patients, regardless of their background. In addition, these companies can work with community organizations and patient advocacy groups to engage with underrepresented populations and educate them about clinical trial opportunities.

However, part of it is a pipeline and representation problem. Underrepresented populations are also not seen enough in the hospitals, laboratories and the clinical research centers to encourage and educate those that need the services the most. An example of this is Johnson and Johnson's initiative to improve physician diversity. This helps to increase participation in clinical trials. We need to increase the diversity of the clinical trial workforce at all levels.

Another solution is to ensure that pricing and reimbursement policies do not create barriers to access for underserved communities. Many life-saving treatments are prohibitively expensive for low-income patients, leading to disparities in access and outcomes. By working with policymakers and insurance providers to develop pricing models that are more affordable for all patients, pharmaceutical and biotech companies can help address this issue.

One success story is Pfizer's partnership with GAVI to develop a vaccine for pneumococcal disease, a leading cause of death among children in developing countries. This partnership helped make the vaccine available at an affordable price to low-income countries, and has saved millions of lives. Through partnerships with government and nonprofit organizations, pharmaceutical and biotech companies can expand access to this life-saving vaccine and help save millions of lives.

Health Equity is an urgent issue that requires the attention and action of the pharmaceutical and biotech industries. There is a medical, business and legal case for health equity so more pharmaceutical and biotech companies should be paying attention. By increasing the representation of diverse populations in clinical trials and working to ensure that pricing and reimbursement policies do not create barriers to access for underserved communities, these companies can help close the gap in healthcare outcomes and improve the health and well-being of all patients. With the right partnerships and investments, pharmaceutical and biotech companies can make a significant impact in the fight for health equity.

What are you doing towards achieving health equity in clinical trials? It takes a village so let's collaborate!

"Prioritizing Health Equity in Clinical Trials and Research: The Key to Closing the Gap in Health Disparities"
July 1, 2022 at 4:00 AM
by Dr. Lola Adeyemi
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Clinical trials and research are integral for advancing medical knowledge and developing new treatments and therapies for a variety of health conditions. They have significantly contributed to advancements in medicine and saved millions of lives . Now more than ever, it is crucial to ensure that these studies are conducted with a focus on health equity to ensure that all individuals, regardless of their demographic or socioeconomic background, have access to high-quality healthcare. Unfortunately, health equity is often not prioritized in clinical trials and research, leading to disparities in health outcomes.

One of the main reasons for this is the lack of diversity in study populations. According to a study by the FDA, minorities and women are underrepresented in clinical trials, with only 7% of participants being African American, 7% Hispanic, and 2% Asian. This lack of representation has led to significant gaps in our understanding of how treatments and therapies work in different demographic groups, resulting in limited access to effective treatments for underserved populations.

One success story is the inclusion of diverse populations in the clinical trials for the COVID-19 vaccine. According to the National Institutes of Health, the clinical trials for the Pfizer-BioNTech vaccine included a diverse population of 44% participants from communities of color, and the Moderna vaccine trials included 37% participants from communities of color. This deliberate effort to include diverse populations in the trials has resulted in higher vaccine confidence and uptake among these communities.

Another issue is the lack of access to clinical trials and research studies for underserved populations. According to the National Institute on Minority Health and Health Disparities, minorities are less likely to participate in clinical trials due to barriers such as lack of transportation, mistrust of medical research, and inadequate access to healthcare providers who are aware of ongoing studies. This lack of representation in clinical trials can further perpetuate disparities in health outcomes.

One success story is the community-based approach taken by the National Cancer Institute's Community Oncology Research Program. This program provides access to clinical trials for cancer patients in community settings, increasing participation among underrepresented populations. In one study, the program increased participation by 500% among African American patients and 200% among Hispanic patients.

Addressing health equity in clinical trials and research requires a concerted effort from all stakeholders involved in the process. One solution is to increase diversity in study populations by actively recruiting individuals from underrepresented communities. The National Institute on Aging successfully increased the diversity of its Alzheimer's disease clinical trials by partnering with community organizations and recruiting participants from underrepresented communities. Another solution is to improve access to clinical trials and research studies for underserved populations by providing financial support for participation and increasing awareness of ongoing studies through community outreach programs. The University of Texas MD Anderson Cancer Center successfully increased participation among underserved populations by providing financial assistance for transportation, lodging, and meals during clinical trial participation. Several pharmaceutical companies provide support for clinical trial participants to cover their time and expenses and have also begun programs that address health equity, AstraZeneca, Johnson & Johnson and Novartis are great examples however they are the exception and not the rule.

In closing, prioritizing health equity in clinical trials and research is crucial for closing the gap in health disparities. By increasing diversity in study populations and improving access to clinical trials and research studies for underserved populations, we can ensure that all individuals have access to high-quality healthcare. The success stories mentioned above demonstrate that deliberate efforts to address health equity can lead to increased participation among underrepresented populations and improved health outcomes. By continuing to prioritize health equity in clinical trials and research, we can work towards a more equitable healthcare system for all.

What are you doing towards achieving health equity in clinical trials? It takes a village so let's collaborate!

"How Health Disparities are Affecting Communities Worldwide and What Can Be Done to Address Them"
February 1, 2022 at 5:00 AM
by Dr Lola Adeyemi
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Health disparities are an ongoing public health issue affecting communities worldwide. These disparities refer to the differences in health outcomes experienced by different populations due to various factors such as socioeconomic status, race, ethnicity, and geographic location. These disparities have significant consequences for individuals and society as a whole, including reduced quality of life, increased healthcare costs, and decreased economic growth.

One of the major causes of health disparities is poverty. Poverty can lead to inadequate nutrition, exposure to environmental toxins, and limited access to healthcare, resulting in chronic health problems. This issue is particularly prevalent in low-income countries, where access to basic healthcare is limited, and many people lack access to clean water, sanitation, and adequate housing.

Another major contributor to health disparities is discrimination. Discrimination can prevent individuals from accessing healthcare services and contribute to chronic stress, which can lead to a range of health problems. Discrimination based on race, ethnicity, gender, sexual orientation, and other factors can also affect health outcomes and contribute to disparities in healthcare access and outcomes.

The COVID-19 pandemic has also highlighted the significant impact of health disparities on communities worldwide. The pandemic has disproportionately affected certain populations, including low-income communities and communities of color. These communities often face barriers to accessing healthcare services, live in crowded housing, and work in jobs that expose them to greater risk of infection.

Addressing health disparities requires a multifaceted approach that involves addressing social determinants of health, improving access to healthcare, and reducing discrimination and social isolation. For example, improving access to healthcare can involve expanding health insurance coverage, increasing the number of healthcare providers in underserved areas, and reducing language barriers that may prevent individuals from accessing care.

Addressing social determinants of health can involve implementing policies to reduce poverty, improve education, and reduce exposure to environmental toxins. Reducing discrimination and social isolation can involve implementing policies to address systemic racism, promoting cultural competence among healthcare providers, and implementing programs to reduce social isolation among vulnerable populations.

Successful interventions have been implemented to address health disparities. For example, the Affordable Care Act in the United States has expanded health insurance coverage and reduced racial and ethnic disparities in healthcare access and utilization. In Australia, the "Close the Gap" initiative aims to reduce health disparities between Aboriginal and Torres Strait Islander populations and non-Indigenous Australians by improving access to healthcare, reducing exposure to environmental toxins, and addressing social determinants of health.

There have been significant resources expended on health disparities but there is still so much to do. The solution requires a multifaceted approach that involves addressing social determinants of health, improving access to healthcare, and reducing discrimination and social isolation but also working in partnerships and collaboratively.

What are you doing towards improving health disparities in your community or organization? It takes a village so let's collaborate!

Understanding Health Equity
December 1, 2021 at 4:00 AM
by Dr. Lola Adeyemi
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Health Equity is a concept that has become increasingly important in the healthcare sector in recent years. It refers to the idea that everyone should have the same opportunity to achieve good health, regardless of their race, ethnicity, socioeconomic status, or other social determinants of health. For example, if two individuals have the same health condition, they should receive the same level of care, regardless of their socioeconomic status or any other factor.

Understanding Health Equity

To better understand health equity, it is important to distinguish it from health equality. Health equality refers to everyone having the same level of health status, but health equity recognizes that some people face more barriers to good health than others and aims to address those barriers. These barriers are often the result of social determinants of health, such as access to healthcare, housing, education, and healthy food.

For example, a person who lives in poverty may not have access to healthy food or safe housing, which can lead to health problems like obesity or respiratory issues. A person who lives in an area with high levels of air pollution may also experience health problems. Health equity aims to address these social determinants of health to ensure that everyone has an equal opportunity to achieve good health.

Importance of Health Equity

Health equity is important for several reasons. First, it is a matter of social justice. Health disparities that are the result of social determinants of health are often avoidable and unfair. For example, African American infants are more than twice as likely as white infants to die before their first birthday due to factors such as poverty and discrimination. Addressing health disparities can help promote social justice and ensure that everyone has an equal opportunity to live a healthy life.

Second, health equity is important for economic reasons. Health disparities lead to increased healthcare costs, lost productivity, and lower economic growth. For example, a National study on The Economic Burden of Health Inequalities in the United States found that eliminating racial and ethnic health disparities in the U.S. could save $1.24 trillion in direct and indirect costs. By addressing health disparities, we can promote economic growth and reduce healthcare costs.

Third, health equity is important for public health reasons. Health disparities can lead to the spread of infectious diseases and the development of chronic conditions. For example, people living in poverty are more likely to have diabetes or heart disease, which can have serious public health consequences. Addressing health disparities can improve population health and reduce the burden of disease.

Achieving Health Equity

Achieving health equity requires a multifaceted approach with a societal responsibility. It involves addressing social determinants of health, such as access to healthcare, housing, education, and healthy food. For example, a program that provides free healthy food to families living in food deserts can help address disparities in nutrition and reduce the risk of chronic diseases.

It also involves addressing structural racism and discrimination, which are major contributors to health disparities. For example, a study found that black patients with identical symptoms as white patients were less likely to be given pain medication in emergency rooms. Addressing implicit bias in healthcare can help promote health equity.

In addition, achieving health equity requires community engagement and collaboration across sectors, including healthcare, education, housing, and employment. For example, a partnership between a hospital and a local community organization can provide healthcare services and resources to underserved populations.

Innovation is critical to achieving health equity, constantly seeking new ways to improve health care and change the status quo.

One approach to achieving health equity is through health equity impact assessments (HEIAs). HEIAs are tools that assess the potential impact of policies, programs, and initiatives on health equity. They can identify unintended consequences and ensure that policies and programs are designed to promote health equity.

Conclusion

Health equity is a fundamental human right. Achieving health equity requires addressing social determinants of health, addressing structural racism and discrimination, engaging communities, and collaborating across sectors. By working towards health equity, we can improve population health, reduce healthcare costs, and promote social justice.

What are you doing towards achieving health equity in your community or organization? It takes a village so let's collaborate!

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The Six Biggest Benefits of Having a Coach
June 25, 2019 at 12:00 AM
by Dr Lolade Adeyemi
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I'm Dr. Lolade Adeyemi, and I'm an entrepreneur extraordinaire who is passionate about helping people achieve their dreams. I truly believe with the right guidance, anything is possible. I know the lasting impact a coach or mentor can have on the people they work with, and I want to share them with you.
 

I've picked out the six best benefits of having a coach and outlined them below.
 

1. Your Coach Can See Your Potential
 

  • Your coach won't know your weaknesses unless you share them, but they'll see your potential. Your coach can help you envision yourself in the future when you've accomplished your goals, and you're doing what you dream of doing. They'll help you create your potential and push you to live up to it.
     

2. Your Coach is a Confidante with Your Best Interests in Mind

  • Having a coach gives you someone who is non-judgemental and experienced in your corner. They'll give you advice if you ask for it, and your coaches can act as a sounding board. They concentrate solely on your best interests. Also, you'll get constant one-on-one attention from someone who wants you to succeed.
     

3. Your Coach Will Hold You Accountable
 

  • Once you set goals or plans, your coach will hold you accountable for them. They can give you the push you need to achieve them. They can also help you set a strategy to meet your goals. Accountability may be homework, inspiration, encouragement, or motivation. Your coach may check in with you each time you meet to see how well you're doing with your goals.
     

4. Your Coach Will Help You Expand Your Thinking
 

  • Did you know that a lot of the limitations you have you place on yourself? Maybe your fears are holding you back. Whatever the reason, your coach will help you expand your thinking and move past it. They may ask you some tough questions to get to the root of the problem. But, they can then help you solve it and remove your limitations.
     

5. Your Coach Can Build Your Personal Awareness

  • Your coach may give you suggestions to improve yourself. But, they can help you become more personally aware of your weaknesses or blind spots. Your coach can see them, point them out, and help you turn them into strengths. In turn, this increases your personal awareness.
     

6. Your Coach Provides Support for Skill Development
 

  • Having constant support to help you improve your skills is critical. Your coach can help you pick a skill, set up an improvement plan, and execute it. It could be something like communication or team building. Anything that you feel you could use further development in, your coach can help.
     

Contact Dr. Lolade Adeyemi to Book Your Session Today!

Are you ready to get inspired? Maybe you'd like advice or guidance from someone who has been in your place and transformed a company into a thriving entity. Either way, I can't wait to hear from you! 

Get in touch with me today! 

Exploring the benefits of using a keynote speaker
May 22, 2019 at 12:00 AM
by Dr Lolade Adeyemi
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Today, it’s easier than ever to try and establish yourself as an entrepreneur. Thanks to the Internet, some people can start a business in a matter of days. But then you need to make sure your business keeps existing. In my experience, this is usually where people start to lose their zest for the process, resulting in them failing to reach their full potential or propel their business as far as it could go.

If you or your business are feeling stagnant, it’s worth finding new ways to revisit your enthusiasm for your work. As an experienced keynote speaker, I’m here to explain why hiring me to speak at your next event comes with multiple benefits. In addition to giving you and your workforce a morale boost, I can broaden your business’s reach.

Your workforce benefits from a fresh perspective

When workers start to feel stagnant or uninspired, they often require an outsider’s point of view to refresh their perspective. As a keynote speaker, I focus on banishing the status quo and adopting forward-thinking solutions to everyday problems. Although you may try your best to enhance your workforce morale, sometimes they need to hear encouraging words from an impartial party. When I inject a new sense of enthusiasm into your workplace, this will reflect in their day-to-day efforts.

Your event attracts a bigger audience

If your business is hosting an event that external participants can sign up for, attracting a significant audience feels challenging. One of the biggest benefits of using a keynote speaker is the ability to advertise an impressive timetable to prospective attendees. When you advertise your keynote speaker on social media, you should find that your ticket sales rise faster than when you simply focus on using your company’s staff. As a result, you’ll broaden your business’s reach.

Defeating boredom becomes possible

One of the main reasons any employee falls into stagnant patterns is because their workplace has become boring. Although they likely entered the company brimming with enthusiasm, they’re familiar with how it works and the benefits of being there have caused them to lose sight of why they wanted the role at all. As a keynote speaker working in different countries, I break up the routines of everyday business events and make them inspiring. When your employees have the chance to step away from their usual routine, they’ll carry a fresh sense of creativity into their work.

You can inspire change

As a business owner or employer, you may spend a lot of your time trying to motivate your employees. Unfortunately, although your efforts are well-intentioned, they may fall on deaf ears as your employees have adapted to your techniques. In contrast, when they hear inspiring words from someone new, they may make the changes you crave.

Why hire me as your keynote speaker?

After graduating from medical school in Nigeria, I pursued master’s degrees in Public Health and in Sustainability & Environmental Management from Johns Hopkins University and Harvard University respectively . Since then, I have worked as a clinician & entrepreneur, but I’ve always had a thirst for inspiring others. Alongside helping to reshape the healthcare system in my home country, I help fellow physicians, professionals and entrepreneurs reach their full potential with my coaching and keynote speaking services. As an outsider, I’m able to identify what’s holding you and your business back and I can develop the mechanisms that push you forward again.

To learn more about my services as a keynote speaker for your organization or to discuss hiring me as your business coach, call 443 538 9603.